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. 2020 Dec 16;554:83–88. doi: 10.1016/j.virol.2020.12.001

Table 1.

Amino acid residues that form hydrogen bonds between GCs and ACE2 and RBD of 2019-nCoV spike protein.

GC	ACE2	RBD of 2019-nCoV spike protein
DEX	LYS353^a, GLY354	GLY496, GLN498^a
BET	THR324, GLY354, ASN330	SER494, GLY496, TYR505
TRI	ASP30^a, GLN35	TYR449, GLY496
MET	THR324, GLY354, ARG357^a	GLN493, GLY496, TYR505
FLO	THR27, GLN76	GLY496, GLN498^a
FLD	ASP30^a	GLN493, GLY496
HYD	THR324, LYS353, GLY354	SER494, GLY496, TYR505

^a

Amino acid residues are the active sites of ACE2 binding to RBD during virus invasion.