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. 2020 Dec 16;18:198. doi: 10.1186/s12915-020-00932-y

Publisher Correction: Spontaneous regression of micro-metastases following primary tumor excision: a critical role for primary tumor secretome

Lee Shaashua 1,#, Anabel Eckerling 1,#, Boaz Israeli 1, Gali Yanovich 2, Ella Rosenne 1, Suzana Fichman-Horn 3, Ido Ben Zvi 4, Liat Sorski 1, Rita Haldar 1, Ronit Satchi-Fainaro 5, Tamar Geiger 2, Erica K Sloan 6, Shamgar Ben-Eliyahu 1,
PMCID: PMC7745392  PMID: 33327952

Correction to: BMC Biol 18, 163 (2020)

https://doi.org/10.1186/s12915-020-00893-2

The original publication of this article [1] contained an incorrect version of figure 4, and an incorrect version of figure S4 in Additional file 1. The wrong version of both files, which contained an incorrect color legend, was accidentally used during typesetting of the article.

In this correction article the correct and incorrect version of figure 4 are published along with the updated Additional file 1.

The original article has been updated.

graphic file with name 12915_2020_932_Figa_HTML.jpg

Incorrect figure 4.

Correct Figure 4.

Fig. 4.

Fig. 4

Associations between levels of Serpin E1, IL-8, MIF, and PDGF-AA and survival in breast cancer patients. The METABRIC dataset was used to assess the association between expression levels of Serpin E1 (a), IL-8 (b), PDGF-AA (c), MIF (d) and the mean signature levels of all 4 factors (median of the mean of normalized expression levels of the four factors) (e), with 10-year survival. Protein levels were classified as higher or lower than the median, and the association to 10-year survival was assessed by the Kaplan-Meier analysis (n = 952 per group). p value was calculated using two-sided log rank test

Supplementary Information

12915_2020_932_MOESM1_ESM.docx (246.6KB, docx)

Additional file 1: Fig. S1. Excision of the primary tumor elicits gradual regression of early-stage metastases. Table S1. Cytokines pointed out by the cytokine array. Fig. S2. ELISA validation of in-vitro tumor secretion of the chosen cytokines. Fig. S3. Elevated levels of Serpin E1, IL-8, MIF and PDGF-AA are correlated to poor survival in lung cancer patients. Fig. S4. Associations between levels of DKK1, IL-6, M-CSF and LIF and survival in breast cancer patients.

Footnotes

Lee Shaashua and Anabel Eckerling contributed equally to this work.

Reference

  • 1.Shaashua L, Eckerling A, Israeli B, et al. Spontaneous regression of micro-metastases following primary tumor excision: a critical role for primary tumor secretome. BMC Biol. 2020;18:163. doi: 10.1186/s12915-020-00893-2. [DOI] [PMC free article] [PubMed] [Google Scholar]

Associated Data

This section collects any data citations, data availability statements, or supplementary materials included in this article.

Supplementary Materials

12915_2020_932_MOESM1_ESM.docx (246.6KB, docx)

Additional file 1: Fig. S1. Excision of the primary tumor elicits gradual regression of early-stage metastases. Table S1. Cytokines pointed out by the cytokine array. Fig. S2. ELISA validation of in-vitro tumor secretion of the chosen cytokines. Fig. S3. Elevated levels of Serpin E1, IL-8, MIF and PDGF-AA are correlated to poor survival in lung cancer patients. Fig. S4. Associations between levels of DKK1, IL-6, M-CSF and LIF and survival in breast cancer patients.


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