To the Editor
Reported cutaneous manifestation incidence during COVID‐19 infection varied between countries, and a recent review showed a worldwide mean incidence of 1.7%. 1 These manifestations are polymorphic and vary dependently on the disease severity. 2 Few pityriasis rosea (PR) and PR‐like eruptions have been reported during COVID‐19 infection. 3 , 4
Herein, we report a case of PR‐like eruption as a leading manifestation of COVID‐19.
A 26‐year‐old woman with no previous medical history presented to our dermatology clinic for 1‐week history of erythematous scaly annular and oval papules over the trunk in a ‘Christmas tree’ like pattern (Fig. 1a). The eruption was preceded with a herald annular plaque with a peripheral scaling collaret on her right thigh (Fig. 1b). The patient developed fever, cough and myalgia 48 h later. She underwent a PCR test for COVID‐19, which came back positive.
In this case, PR may be directly linked to COVID‐19 infection or to viral reactivation (e.g. HHV6, HHV7 and EBV) as previously reported 5 .
To our knowledge, reports on cutaneous manifestations that precede respiratory symptoms in COVID 19 are scarce. Dermatologists should be aware that cutaneous manifestations can be the presenting complaint of COVID‐19 patients.
Conflicts of interest
Dr. Merhy, Dr Sarkis and Dr Stephan have nothing to disclose.
Funding source
None.
Acknowledgement
The patient in this manuscript has given written informed consent to publication of her case details.
References
- 1. Matar S, Oulès B, Sohier P et al. Cutaneous manifestations in SARS‐CoV‐2 infection (COVID‐19): a French experience and a systematic review of the literature. J Eur Acad Dermatol Venereol 2020; 34: e686–e689. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 2. Freeman EE, McMahon DE, Lipoff JB et al. The spectrum of COVID‐19‐associated dermatologic manifestations: an international registry of 716 patients from 31 countries. J Am Acad Dermatol 2020; 83: 1118–1129. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 3. Martín Enguix D, Salazar Nievas MDC, Martín Romero DT. Pityriasis rosea Gibert type rash in an asymptomatic patient that tested positive for COVID‐19. Med Clin Engl Ed 2020; 155: 273. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 4. Ehsani AH, Nasimi M, Bigdelo Z. Pityriasis rosea as a cutaneous manifestation of COVID‐19 infection. J Eur Acad Dermatol Venereol 2020; 34: e436–e437. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 5. Drago F, Ciccarese G, Rebora A, Parodi A. Human herpesvirus‐6, ‐7, and Epstein‐Barr virus reactivation in pityriasis rosea during COVID‐19. J Med Virol 2021; 93: 1850–1851. [DOI] [PMC free article] [PubMed] [Google Scholar]