Figure S5.

Stimulation-Driven Remapping Controls, Related to Figure 5

(A) Pre-post epoch spatial activity profile correlation for responsive and unresponsive Start-PCs and Reward-PCs, demonstrating that we did not observe more remapping in responsive neurons (p = 0.14 Start-PC and p = 0.69 Reward-PC, two-sided rank-sum test). (B) Calcium trace peak ΔF/F value location across virtual space for place cells identified during the baseline epoch of stimulation days. (C) Shuffled chance distribution of the number of place cells with peaks inside the reward zone and real data value (red line). Shuffle distribution generated by randomly translating each place cells average ΔF/F trace within the spatial range of the track. (D) Place cell center of mass distributions for all place cells in pre and post epochs of Non-PC stimulation days. (E) Pre-post center of mass shift for Start-PCs and Reward-PCs during Non-PC stimulation sessions. (F) Pre-post center of mass shift for stimulation zone place cells across all session types. (G) Pre-post center of mass shift for all place cells across different session types. (H) Summary of the stimulation zone place cell pre-post center of mass shifts, no differences were found (Kruskal-Wallis test). (I) Summary of the pre-post center of mass shift for all neurons, the shift was different when comparing Reward-PC sessions to all other session types, p = 0.0013, p = 0.0002 and p = 0.0145 for No stim, Start-PC and Non-PC respectively, Kruskal-Wallis with Dunn’s test. (J) Delta lick rate between pre and post equivalent epochs for non-stimulation days. All error bars show SEM.