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Journal of Integrative Bioinformatics logoLink to Journal of Integrative Bioinformatics
. 2020 Jul 20;17(2-3):20200018. doi: 10.1515/jib-2020-0018

Systems Biology Markup Language (SBML) Level 3 Package: Distributions, Version 1, Release 1

Lucian P Smith 1,, Stuart L Moodie 2, Frank T Bergmann 3, Colin Gillespie 4, Sarah M Keating 5, Matthias König 6, Chris J Myers 7, Maciek J Swat 8, Darren J Wilkinson 4, Michael Hucka 9
PMCID: PMC7756622  PMID: 32750035

Abstract

Biological models often contain elements that have inexact numerical values, since they are based on values that are stochastic in nature or data that contains uncertainty. The Systems Biology Markup Language (SBML) Level 3 Core specification does not include an explicit mechanism to include inexact or stochastic values in a model, but it does provide a mechanism for SBML packages to extend the Core specification and add additional syntactic constructs. The SBML Distributions package for SBML Level 3 adds the necessary features to allow models to encode information about the distribution and uncertainty of values underlying a quantity.

Keywords: distributions, modeling, SBML, systems biology, uncertainty


Articles from Journal of Integrative Bioinformatics are provided here courtesy of De Gruyter

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