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The protective effect of flavonoids in cataract formation. The diagram shows the effect of flavonoids on Nrf2 activation, leading to reduced inflammation, oxidative stress, and ROS, involved in cataract development. The figure also highlights Nrf2 modulation by epigenetic factors and the attenuation of MMP expression by flavonoids or by the inhibitory effect of the Nrf2 pathway in NFκB pathway activation.
