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. 2020 Nov 25;8(12):1856. doi: 10.3390/microorganisms8121856

Figure 1.

Figure 1

Phylogenetic analysis of the enterovirus genus. VP1 gene sequences from complete human enterovirus genomes were retrieved from the ViPR database (https://www.viprbrc.org/). Sequences representative of the genomic diversity were selected using CD-HIT [128], with a threshold of 0.90, and subsequently aligned using MAFFT E-INS-i. The phylogenetic tree was generated using RaXML with 100 bootstrap replicates, and then visualized in Archaeopteryx.js on ViPR with leaf nodes color coded by phylogenetic relatedness. Bootstrap support values of 50 or larger are shown in the tree. Major monophyletic groups are labeled with the major types in the group. Major types are defined as those with 50 or more genomes in the case of EV-A and EV-C, and 200 or more genomes in the case of EV-B.