Table 2.
Association between fetal biometry at 22–24 gestational weeks and subsequent gestational diabetes (GDM).
| Main Exposure | GDM, n (%) |
Crude OR (95% CI) |
Adjusted OR †
(95% CI) |
Adjusted OR ‡
(95% CI) |
|---|---|---|---|---|
| AC | ||||
| <10th percentile (n = 2442) | 436 (17.9) | 0.94(0.84, 1.04) | 1.00 (0.90, 1.12) | 1.00 (0.89, 1.11) |
| 10th–90th percentile (n = 36,036) | 6773 (18.8) | 1.0 (reference) | ||
| >90th percentile (n = 5701) | 1115 (19.6) | 1.05 (0.98, 1.12) | 0.99 (0.92, 1.06) | 0.98 (0.91, 1.05) |
| HC | ||||
| <10th percentile (n = 4219) | 856 (20.3) | 1.11 (1.02, 1.20) * | 1.17 (1.08, 1.27) * | 1.15 (1.06, 1.25) * |
| 10th–90th percentile (n = 35,299) | 6599 (18.7) | 1.0 (reference) | ||
| >90th percentile (n = 4661) | 869 (18.6) | 1.00 (0.92, 1.08) | 0.95 (0.88, 1.03) | 0.97 (0.90, 1.05) |
| FL | ||||
| <10th percentile (n = 4069) | 842 (20.7) | 1.14 (1.05, 1.23) * | 1.21 (1.12, 1.31) * | 1.17 (1.08, 1.27) * |
| 10th–90th percentile (n = 37,350) | 6948 (18.6) | 1.0 (reference) | ||
| >90th percentile (n = 2760) | 534 (19.3) | 1.05 (0.95, 1.16) | 1.02 (0.92, 1.12) | 1.01 (0.91, 1.11) |
| EFW | ||||
| <10th percentile (n = 3010) | 599 (19.9) | 1.09 (0.99, 1.19) | 1.16 (1.05, 1.27) * | 1.13 (1.03, 1.25) * |
| 10th–90th percentile (n = 33,614) | 6245 (18.6) | 1.0 (reference) | ||
| >90th percentile (n = 7555) | 1480 (19.6) | 1.07 (1.00, 1.14) * | 1.01 (0.94, 1.07) | 1.00 (0.94, 1.07) |
* p < 0.05 † Adjusted for maternal age, parity and fetal sex. ‡ Adjusted for maternal age, parity, fetal sex, pre-pregnancy height and pre-pregnancy BMI. OR = odds ratio; AC = abdominal circumference; HC = head circumference; FL = femur length; EFW = estimated fetal weight.