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Furosemide solubility values (µg/mL) at the tree pH values 1.0, 4.0, and 7.5, at 37 °C (upper panel), and at room temperature (25 °C; lower panel), as well as the corresponding dose number (D0) calculated for an 80-mg dose. Data presented as mean ± SD; n = 6.
| At 37 °C | ||
| pH | Solubility (µg/mL) | Corresponding D0 |
| 1 | 19.4 ± 3.7 | 16.5 |
| 4 | 65.5 ± 9.0 | 4.8 |
| 7.5 | 8340.1 ± 81.6 | 0.04 |
| At 25 °C | ||
| pH | Solubility (µg/mL) | Corresponding D0 |
| 1 | 40.3 ± 16.2 | 7.9 |
| 4 | 56.7 ± 12.2 | 5.6 |
| 7.5 | 8550.6 ± 149.4 | 0.04 |
