TABLE 1.
Clinical characteristics of study participantsa
| Group | Inclusion criteria | No. of participants | Median age (yrs) (IQR) | No. of females/total no. of participants | Median no. of CD4 cells (IQR) | Mean % CD4 cells (IQR) | VL (cp/ml) | Median time on ART (yrs) (IQR) |
|---|---|---|---|---|---|---|---|---|
| Prog | Vertically HIV infected, >5 yrs of age, ART naive, CD4 count of <500 cells/mm3 |
23 | 13.1 (9.1–16.8) | 11/23 | 378 (251–442) | 17 (9–21) | 52,000 (7,800–140,000) | None |
| PNP | Vertically HIV infected, >5 yrs of age, ART naive, CD4 count of >750 cells/mm3 |
10 | 9.5 (7.5–12.1) | 5/10 | 907 (845–1,076) | 34.5 (31–43) | 50,500 (875–72,750) | None |
| ART treated | Vertically HIV infected, >5 yrs of age, ART treated, VL of <20 cp/ml |
13 | 10.1 (8.5–11.7) | 6/13 | 741 (500–939) | 30 (22–40) | All <20 | 3.9 (0.8–5.4) |
| HIV− | HIV negative, >5 yrs of age | 10 | 11.5 (8.6–14.5) | 5/10 | ND | ND | ND | None |
a
Median values and interquartile ranges are shown for each clinical parameter. Prog, progressors; HIV−, HIV negative; PNP, pediatric nonprogressor; VL, viral load; cp/ml, HIV RNA copies per milliliter of plasma; ND, not determined.