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Summary of cytotoxicity of BN and the betulin glycoconjugates.
| Compound | Activity IC50 [µM] a,b | |
|---|---|---|
| MCF-7 | NHDF | |
| 1 | 12.40 ± 0.14 | 11.60 ± 0.22 |
| 15a | 65.28 ± 0.68 | 60.62 ± 0. 64 |
| 15b | 47.70 ± 0.72 | 47.61 ± 0.86 |
| 16a | 29.77 ± 0.52 | 29.82 ± 0.45 |
a Cytotoxicity was evaluated using the CCK-8 assay; b Incubation time 48 h.
