Xuefeng Niu
Xuefeng Niu
1
State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
1,†,
Song Li
Song Li
2
Jiangsu Industrial Technology Research Institute (JITRI), Applied Adaptome Immunology Institute, Nanjing, China
3
iRepertoire Inc., Huntsville, AL, United States
2,3,†,
Pingchao Li
Pingchao Li
4
Guangzhou Regenerative Medicine and Health-Guangdong Laboratory (GRMH-GDL), Guangdong Laboratory of Computational Biomedicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
4,
Wenjing Pan
Wenjing Pan
3
iRepertoire Inc., Huntsville, AL, United States
5
HudsonAlpha Institute for Biotechnology, Huntsville, AL, United States
3,5,
Qian Wang
Qian Wang
4
Guangzhou Regenerative Medicine and Health-Guangdong Laboratory (GRMH-GDL), Guangdong Laboratory of Computational Biomedicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
4,
Ying Feng
Ying Feng
1
State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
1,
Xiaoneng Mo
Xiaoneng Mo
6
Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou, China
6,
Qihong Yan
Qihong Yan
4
Guangzhou Regenerative Medicine and Health-Guangdong Laboratory (GRMH-GDL), Guangdong Laboratory of Computational Biomedicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
4,
Xianmiao Ye
Xianmiao Ye
4
Guangzhou Regenerative Medicine and Health-Guangdong Laboratory (GRMH-GDL), Guangdong Laboratory of Computational Biomedicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
4,
Jia Luo
Jia Luo
4
Guangzhou Regenerative Medicine and Health-Guangdong Laboratory (GRMH-GDL), Guangdong Laboratory of Computational Biomedicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
4,
Linbing Qu
Linbing Qu
4
Guangzhou Regenerative Medicine and Health-Guangdong Laboratory (GRMH-GDL), Guangdong Laboratory of Computational Biomedicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
4,
Daniel Weber
Daniel Weber
3
iRepertoire Inc., Huntsville, AL, United States
3,
Miranda L Byrne-Steele
Miranda L Byrne-Steele
3
iRepertoire Inc., Huntsville, AL, United States
3,
Zhe Wang
Zhe Wang
2
Jiangsu Industrial Technology Research Institute (JITRI), Applied Adaptome Immunology Institute, Nanjing, China
2,
Fengjia Yu
Fengjia Yu
2
Jiangsu Industrial Technology Research Institute (JITRI), Applied Adaptome Immunology Institute, Nanjing, China
2,
Fang Li
Fang Li
6
Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou, China
6,
Richard M Myers
Richard M Myers
5
HudsonAlpha Institute for Biotechnology, Huntsville, AL, United States
5,
Michael T Lotze
Michael T Lotze
7
Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, United States
7,
Nanshan Zhong
Nanshan Zhong
1
State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
1,
Jian Han
Jian Han
2
Jiangsu Industrial Technology Research Institute (JITRI), Applied Adaptome Immunology Institute, Nanjing, China
3
iRepertoire Inc., Huntsville, AL, United States
5
HudsonAlpha Institute for Biotechnology, Huntsville, AL, United States
2,3,5,*,
Ling Chen
Ling Chen
1
State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
4
Guangzhou Regenerative Medicine and Health-Guangdong Laboratory (GRMH-GDL), Guangdong Laboratory of Computational Biomedicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
6
Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou, China
1,4,6,*
1
State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
2
Jiangsu Industrial Technology Research Institute (JITRI), Applied Adaptome Immunology Institute, Nanjing, China
3
iRepertoire Inc., Huntsville, AL, United States
4
Guangzhou Regenerative Medicine and Health-Guangdong Laboratory (GRMH-GDL), Guangdong Laboratory of Computational Biomedicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
5
HudsonAlpha Institute for Biotechnology, Huntsville, AL, United States
6
Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou, China
7
Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, United States
Approved by: Frontiers Editorial Office, Frontiers Media SA, Switzerland
✉*Correspondence: Ling Chen, chen_ling@gibh.ac.cn; Jian Han, jhan@hudsonalpha.org
†These authors have contributed equally to this work
This article was submitted to Viral Immunology, a section of the journal Frontiers in Immunology
Received 2020 Nov 26; Accepted 2020 Nov 27; Collection date 2020.
Keywords: COVID-19, SARS-CoV-2, T cell receptor, B cell receptor, immune repertoire, biomarker
Copyright © 2020 Niu, Li, Li, Pan, Wang, Feng, Mo, Yan, Ye, Luo, Qu, Weber, Byrne-Steele, Wang, Yu, Li, Myers, Lotze, Zhong, Han and Chen
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
