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Schematic representation of AdCAR NK-92 function and structure. The NK-92 cells were generated with an adapter CAR recognizing a neoepitope on biotinylated antibodies which are directed against surface antigens on tumor cells (a). Schematic representation of the lentiviral transfer plasmid encoding the AdCAR construct comprising a CD28 co-stimulatory domain and a CD34 tag sequence (b), which was provided by Miltenyi Biotec.
