TABLE 2.

Treatment-Related Adverse Events (n = 39)

Toxicity	All Grades, No. (%)	Grade ≥ 3, No. (%)
Fatigue	23 (59)	4 (10.3)
Hypertension	21 (53.8)	12 (30.8)
AST increased	20 (51.3)	4 (10.3)
ALT increased	17 (43.6)	4 (10.3)
Thrombocytopenia	15 (38.5)	2 (5.1)
Hand foot skin reaction	14 (35.9)	4 (10.3)
Anemia	12 (30.8)	2 (5.1)
Nausea	12 (30.8)	1 (2.6)
Vomiting	9 (23.1)	0
Diarrhea	6 (15.4)	0
Rash, acneiform	3 (7.7)	0
Thromboembolic event	2 (5.1)	2 (5.1)

Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase.