Table 3.

The groupings of chemical descriptors

Group	Size	References
Atom-based	19	Lusci et al. (2013); Avdeef, 2020; Yan et al., 2004,Schroeter et al., (2007); Tang et al., 2020; Hou et al., (2004)
Ring-based	6	Avdeef, 2020; Yan et al., 2004; Tang et al., 2020
Bond-based	9	Jorgensen and Duffy (2002); Lusci et al. (2013); Delaney (2004); Avdeef, 2020,Yan et al., 2004; Tang et al., 2020; Raevsky et al., 2015
LogP	1	Lusci et al. (2013); Delaney (2004); Avdeef, 2020; Yan et al., 2004,Schroeter et al., (2007); Raevsky et al., 2015; Ali et al., (2012)
Topological	18	Jorgensen and Duffy (2002); Huuskonen (2000); Avdeef, 2020; Yan et al., 2004,Schroeter et al., (2007); Raevsky et al., 2015; Ali et al., (2012)
E-state indices	70	Avdeef, 2020, Huuskonen, 2000, Tetko et al., 2001