Figure 4. SK andits derivatives reduced the level of NLRP3 inflammasome activation in colonic tissues.

(A) Protein levels of NLRP3, ASC, caspase-1, and IL-1β were determined by Western blotting. β- a ctin was used as a control. (B) Relative protein expression ratio was determined by densitometry and normalized to β- a ctin. Each point represents the mean ± S.E.M. from three replicates (*p < 0.05, **p < 0.01 versus control group; # p < 0.05, ## p < 0.01 versus DSS-treated group).