Twist promotes tumor metastasis in basal-like breast cancer by transcriptionally upregulating ROR1: Erratum

We noticed an error in Figure 4G, where the HE (200 x) for shROR1+Twist was misplaced with the same HE picture for Twist. The figure with the error corrected is shown below. The correction made in this erratum does not affect the original conclusions or any part of the text and figure legends. The authors wish to apologize for any inconvenience or misunderstanding that this error may have caused.

Figure 4.

The promotion of cell migration, invasion and cancer metastasis after Twist overexpression primarily depends on ROR1. (A-B) The indicated molecules were analyzed by Western blot in the Hs578T and MDA-MB-231 cells stably expressing control, ROR1 shRNA, Twist, or both, as indicated. (C-F) Cell migration and invasion were determined in the indicated stable cell lines. The results are expressed as the mean ± SD of three independent experiments. * P < 0.05, ** P < 0.01 and *** P < 0.001 using Student's t-test. (G-H) An in vivo lung metastasis model was established in nude mice using MDA-MB-231 cells stably expressing control, ROR1 shRNA, Twist, or both, as indicated. (G) Representative results of gross and H&E staining (middle scale: 40×; right scale: 200×) of metastatic lung nodules. Scale bars, 40×,500μm; 200×,100μm. (H) Illustration of the statistical results (n = 6). The results are expressed as the mean ± SD. * P < 0.05, *** P < 0.001 using Student's t-test.