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Oxford University Press - PMC COVID-19 Collection logoLink to Oxford University Press - PMC COVID-19 Collection
. 2020 Dec 29:ciaa1895. doi: 10.1093/cid/ciaa1895

Previous dengue infection and mortality in COVID-19

Odilson M Silvestre 1,, Letícia R Costa 1, Bianca V R Lopes 1, Mariana R Barbosa 1, Kárenn K P Botelho 1, Kelvyn L C Albuquerque 1, Anna G S Souza 1, Lorran A Coelho 1, Anderson J de Oliveira 1, Cínthia B Barantini 1, Sebastião A V M Neves 1, Wilson Nadruz 2, James H Maguire 3, Miguel M Fernandes-Silva 4
PMCID: PMC7799267  PMID: 33373433

Abstract

We studied 2351 participants with COVID-19, 1177 (50%) reported previous dengue infection. Those without previous dengue had a higher risk of death (hazard ratio: 0.44; 95% CI: 0.22 to 0.89; p = 0.023) in 60-day follow-up. These findings raise the possibility that dengue might induce immunological protection against SARS COV-2.

Keywords: COVID-19, dengue, mortality


Articles from Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America are provided here courtesy of Oxford University Press

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