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. 2021 Jan 1;11(6):2670–2690. doi: 10.7150/thno.53083

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Kidney targeting efficiency of Dex/PFP@LIPs-BMS-α by organ localization in vivo. (A) In vivo targeting efficiency of Dex/PFP@LIPs-BMS-α by organ localization at various intervals (Pre, 4, 8, 16 and 24 h). The photoacoustic signals were shown in red. (B) The photoacoustic threshold of DiR-labeled glucocorticoid nano-delivery system was acquired by PAI system (680-970 nm). (C) Photoacoustic intensities in renal tissue were measured by a Vevo LAZR software at the corresponding point in time. Data are presented as mean ± SD, n = 5, t-test, ****P < 0.0001.