Skip to main content
BJA Education logoLink to BJA Education
. 2020 Feb 7;20(4):139. doi: 10.1016/j.bjae.2020.01.005

Corrigendum to ‘Serotonin syndrome in the perioperative period’ [BJA Education 20 (2020) 10–17]

A Bartakke 1, C Corredor 1,, A van Rensburg 2,3
PMCID: PMC7807954  PMID: 33465184

The authors regret that errors were present in Table 1 of the above article. The correct version of Table 1 appears below:

Table 1.

Differential diagnosis of SS in the perioperative period.

History Clinical
Malignant hyperthermia Family history adverse reactions associated with anesthesia; exposure to halogenated anesthetics or depolarizing NMBAs
  • Hyperthermia >41 C

  • Rigidity

  • Hyporeflexia

  • No myoclonus

Anticholinergic syndrome History of exposure to anticholinergic agent (e.g. tricyclic antidepressants, atropine)
  • Mydriasis

  • Dry mucous membranes

  • Hyperthermia

  • Agitation

  • Decreased bowel sounds

  • Normal muscle tone and reflexes

Opioid toxicity Exposure to opioids
  • Miosis

  • Hypothermia

  • Respiratory depression

  • Hyporeflexia

Neuroleptic malignant syndrome Associated with the use of an antipsychotic (neuroleptic agents)
  • Gradual onset

  • Lead pipe rigidity, fever, dysautonomia.

  • No gastrointestinal symptoms

Perioperative Delirium Acute onset and fluctuating course; multifactorial origin
  • Inattention, disorganized thinking and altered level of arousal.

  • No neuromuscular activation signs (eg, tremor, clonus or hyperreflexia)

Sedative-hypnotic withdrawal History of chronic intake and abrupt cessation of sedatives-hypnotics (e.g., benzodiazepines, baclofen, ethanol, barbiturates)
  • Confusion and agitation.

  • Autonomic dysfunction may be present.

  • No inducible clonus

The authors would like to apologise for any inconvenience caused.


Articles from BJA Education are provided here courtesy of Elsevier

RESOURCES