Skip to main content
BJA Education logoLink to BJA Education
. 2020 Feb 17;20(4):140. doi: 10.1016/j.bjae.2020.02.001

Corrigendum to ‘Basic pharmacology of local anaesthetics’ [BJA Education 20 (2020) 34–41]

A Taylor 1,, G McLeod 1
PMCID: PMC7808059  PMID: 33465173

The authors regret that errors were present in Table 1 of the above article. The correct version of Table 1 appears below:

Table 1 Physicochemical characteristics of local anaesthetics.3−5 MW, molecular weight.

Structural classification MW pKa Protein binding (%) Partition coefficient Onset Elimination half-life (min) Maximum dose without vasoconstrictor (mg kg−1) Maximum dose with vasoconstrictor (mg kg−1)
Cocaine Ester 303 8.6 95 Fast 100 1.5 (topical)
Chloroprocaine Ester 271 9.1 17 Fast 6 11 14
Prilocaine Amide 220 7.7 55 50 Fast 100 6 8
Lidocaine Amide 234 7.8 70 110 Fast 100 3 7 (9 for airway topicalisation)
Mepivacaine Amide 246 7.7 77 42 Fast 115 5 7
Bupivacaine Amide 288 8.1 95 560 Moderate 210 2 2
Ropivacaine Amide 274 8.1 94 230 Moderate 120 3 3
Levobupivacaine Amide 288 8.1 95 Moderate 210 2 2

The authors would like to apologise for any inconvenience caused.


Articles from BJA Education are provided here courtesy of Elsevier

RESOURCES