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. 2020 Dec 29;24(1):102001. doi: 10.1016/j.isci.2020.102001

Table 3.

Studies reporting the efficacy of single- and multi-walled CNTs conjugated with silver and other metals

CNT-metals Type Medical application Species Major conclusions Ref.
AgNPs stabilized with DNA SWCNT Drug delivery A broad range of Gram-positive and -negative bacteria The bactericidal ratio of the AgNP-nanofilm against the major pathogenic organisms was between 57.78% and 78.89% (Subbiah et al., 2011)
AgNPs MWCNT Medical devices E. coli
S. epidermidis
Bacteria viability on the Ag-CNT films decreased by 32% and 13% for S. epidermidis and E. coli, respectively (Jung et al., 2011)
SWCNT Nonspecified E. coli The number of bacteria colonies decreased by 4 log in the presence of Ag-CNT hybrid films (Misra et al., 2012)
MWCNT Medical implants E. coli
S. aureus
Polymer shielded with AgNP-CNT inactivated E. coli and S. aureus by 89.3% and 95%, respectively, and reduced the number of adhered bacteria by 80% for both species (Nie et al., 2017)
MWCNT Medical devices K. pneumoniae
S. aureus
The Ag- plasma polymer fluorocarbon nanocomposite films suppressed the growth and proliferation of bacteria by up 92.2% compared with uncoated films (Cho et al., 2019)
Zn-HA MWCNT Bioimplants B. subtilis
E. coli
S. aureus
Shigella flexneri
Bacterial growth was clearly inhibited by Zn-HA-MWCNT (inhibition zone ≥12 mm) (Sivaraj and Vijayalakshmi, 2018)
PdNPs MWCNT Nonspecified B. subtilis
E. coli
K. pneumoniae
P. aeruginosa
PdNP-MWCNT composites deposited in a polypyrrole matrix showed 65–81.71% biofilm inhibition (Murugesan et al., 2018)

AgNPs, silver nanoparticles; MWCNT, multi-walled carbon nanotubes; PdNPs, palladium nanoparticles; SWCNT, single-walled carbon nanotubes; Zn-HA, Zinc-hydroxyapatite.