Table 2:
Mean changes in health-related quality of life and sleep related outcomes in cancer survivors.
| Intervention Group | Comparison Group | d | 95% CI for d | p* | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Baseline | 12-weeks | Change | 95% CI | Baseline | 12-weeks | Change | 95% CI | ||||||
| Mean±SD | Mean±SD | Mean±SD | Mean±SD | Mean±SD | Mean±SD | ||||||||
| SF-36 | |||||||||||||
| Aggregate physical health | 46.6±8.7 | 52.1±7.9 | 4.3±9.5 | 0.2 | 8.4 | 46.5±7.1 | 47.6±8.9 | 1.2±5.9 | −1.4 | 3.8 | .39 | 0,.78 | .12 |
| Physical functioning | 48.2±7.3 | 52.4±5.0 | 3.1±6.3 | 0.4 | 5.8 | 47.1±7.4 | 47.7±8.6 | 0.3±7.5 | −3.0 | 3.6 | .40 | .01,.80 | .13 |
| Role-physical | 43.5±10.9 | 50.7±9.5 | 6.8±15.3 | 0.2 | 13.4 | 45.9±10.6 | 46.6±10.4 | 1.6±6.5 | −1.3 | 4.5 | .43 | .04,.83 | .085 |
| Bodily pain | 48.8±10.4 | 51.1±11.6 | 1.6±11.0 | −3.1 | 6.4 | 49.8±9.7 | 50.1±11.3 | 0.2±7.3 | −3.0 | 3.4 | .15 | −.24,.54 | .55 |
| General health | 46.1±8.8 | 51.9±7.4 | 5.6±6.7 | 2.7 | 8.5 | 46.5±6.6 | 46.7±6.2 | 0.3±5.1 | −2.0 | 2.6 | .88 | .47,1.29 | .004 |
| Aggregate mental health | 46.8±9.9 | 45.6±8.3 | −0.1±6.2 | −2.7 | 2.6 | 50.2±7.1 | 45.0±11.6 | −4.8±9.3 | −8.9 | −0.6 | .59 | .19,.99 | .06 |
| Mental health | 48.4±9.0 | 51.7±9.2 | 4.0±5.8 | 1.5 | 6.5 | 49.9±9.5 | 49.7±12.5 | 0.4±9.3 | −3.7 | 4.5 | .45 | .06,.85 | .13 |
| Role-emotional | 46.8±9.9 | 49.8±8.9 | 3.7±8.2 | 0.1 | 7.2 | 50.5±6.9 | 48.6±10.0 | −1.4±8.8 | −5.3 | 2.5 | .60 | .20,1.0 | .05 |
| Social functioning | 41.3±9.6 | 28.9±3.3 | −11.9± 8.9 | −15.8 | −8.1 | 43.3±7.8 | 27.4±4.2 | −16.2±7.4 | −19.4 | −12.9 | .51 | .12,.92 | .14 |
| Vitality | 49.4±7.6 | 55.5±8.5 | 6.1±6.5 | 3.3 | 8.9 | 52.4±7.0 | 53.3±10.1 | 1.3±8.8 | −2.6 | 5.2 | .61 | .22,1.02 | .03 |
| FACT | |||||||||||||
| FACT-G total† | 85.0±15.7 | 89.5±15.2 | 4.1±10.4 | −0.6 | 8.9 | 84.6±13.3 | 85.1±16.3 | 0.9±7.8 | −3.0 | 4.8 | .35 | −.05,.75 | .26 |
| Physical well-being | 22.6±4.1 | 24.5±3.8 | 1.4±3.6 | −0.2 | 3.1 | 22.3±6.6 | 23.1±4.4 | −0.3±2.3 | −1.4 | 0.9 | .56 | .17,.97 | .12 |
| Social/family well-being | 22.8±5.0 | 22.5±5.6 | 0.2±2.9 | −1.1 | 1.6 | 21.2±5.2 | 21.4±6.2 | 0.7±3.2 | −0.8 | 2.3 | −.17 | −.56,.22 | .60 |
| Emotional well-being | 18.1±4.9 | 19.6±3.7 | 1.1±3.8 | −0.6 | 2.9 | 20.9±2.5 | 19.9±2.7 | −0.6±2.5 | −1.9 | 0.6 | .54 | .14,.94 | .06 |
| Functional well-being | 21.4±5.6 | 23.0±5.1 | 1.3±3.2 | −0.1 | 2.8 | 20.2±4.8 | 20.7±5.0 | 1.1±3.7 | −0.8 | 2.9 | .08 | −.31,.47 | .68 |
| FACT-B total‡ | 111±20 | 118.1±20.2 | 6.2±13.8 | −0.1 | 12.5 | 109.5± 19.5 | 110.2±22.9 | 0.9±9.7 | −3.9 | 5.7 | .44 | .04,.84 | .16 |
| Breast cancer subscale | 26±6.5 | 28.7±6.3 | 2.1±5.0 | −0.2 | 4.3 | 24.9±7.1 | 25.2±8.0 | 0±3.2 | −1.6 | 1.6 | .48 | .09,.88 | .13 |
| Trial outcome index§ | 70±13.9 | 76.1± 13.6 | 4.8±9.8 | 0.3 | 9.3 | 67.4±14.9 | 68.9±16.0 | 0.8±6.5 | −2.4 | 4.0 | .48 | .09,.88 | .13 |
| Sleep | |||||||||||||
| Sleep disturbance | 46.8±10.3 | 47.0±8.6 | −2.9±6.8 | −6.1 | 0.3 | 49.5±7.6 | 49.5±9.3 | 0.4±7.4 | −3.1 | 3.9 | −.46 | −.86,−.07 | .33 |
| Sleep impairment | 47.6±8.9 | 44.7±9.3 | −3.6±9.8 | −7.8 | 0.6 | 49.5±9.3 | 52.0±10.5 | 2.1±8.5 | −1.7 | 5.8 | −.62 | −1.02,−.22 | .04 |
†
FACTG total=Physical+Social/family+Emotional+Functional
‡
FACTB total=Physical+Social/family+Emotional+Functional+Breast Cancer sub-scale
§
FACTB Trial Outcome Index=Physical+Functional+Breast Cancer sub-scale
*
P-value from the mixed effects regression model and for comparing changes from baseline to 12-weeks between intervention and comparison groups