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Interaction of miR‐210 and SMAD4 is important for cell apoptosis under hypoxia condition. (A) Western blot analysis of SMAD4 levels in stable transfected overexpression and knock‐down cell lines. (B) Flow cytometry analysis of stable transfected cell lines after HR treatment (n = 2, **P < 0.01, ****P < 0.0001). (C,D) Flow cytometry analysis of cell apoptosis of LO2 cells co‐transfected with the indicated oligos after HR treatment (n = 2, **P < 0.01, ***P < 0.001).
