Table 3.
Baseline laboratory measurements of female participants included in the PREVAC trial (pooled for versions 2.0, 3.0, and 4.0)
| Baseline laboratory measurements: females | ||||||||
|---|---|---|---|---|---|---|---|---|
| Age 18+ (n = 1118 ) | Age 12–17 (n = 429) | Age 5–11 (n = 353) | Age 1–4 (n = 276 ) | |||||
| Mean | SD | Mean | SD | Mean | SD | Mean | SD | |
| Biochemistry | ||||||||
| ALT (U/L) | 10.9 | 10.6 | 9.3 | 7.3 | 11.7 | 11.8 | 13.8 | 38.2 |
| AST (U/L) | 14.2 | 9.6 | 14.9 | 6.7 | 20.7 | 11.6 | 28.9 | 30.6 |
| Creatinine (mg/dl) | 0.80 | 0.15 | 0.66 | 0.15 | 0.53 | 0.13 | 0.38 | 0.10 |
| Potassium (mmol/L) | 4.1 | 0.4 | 4.2 | 0.3 | 4.1 | 0.4 | 4.3 | 0.5 |
| Hematology | ||||||||
| White blood cells (x10³/μL) | 6.1 | 2.1 | 6.2 | 1.8 | 7.0 | 1.9 | 8.9 | 2.7 |
| Neutrophils (x10³/μL) | 2.9 | 1.2 | 2.7 | 1.1 | 2.9 | 1.4 | 3.2 | 1.4 |
| Lymphocytes (x10³/μL) | 2.5 | 1.4 | 2.6 | 0.9 | 3.0 | 0.9 | 4.5 | 1.7 |
| Eosinophils (x10³/μL) | 0.21 | 0.26 | 0.26 | 0.37 | 0.35 | 0.43 | 0.39 | 0.64 |
| Monocytes (x10³/μL) | 0.46 | 0.18 | 0.52 | 0.20 | 0.60 | 0.22 | 0.77 | 0.34 |
| Basophils (x10³/μL) | 0.08 | 0.10 | 0.08 | 0.04 | 0.10 | 0.05 | 0.15 | 0.09 |
| Hemoglobin (g/dl) | 12.3 | 1.3 | 12.3 | 1.3 | 11.9 | 1.2 | 10.7 | 1.2 |
| Hematocrit (%) | 37.5 | 3.6 | 37.2 | 3.5 | 36.0 | 3.4 | 33.2 | 3.2 |
| Platelets (x10³/μL) | 264.2 | 71.7 | 288.4 | 76.4 | 321.4 | 87.2 | 394.3 | 111.0 |
| Red blood cells (x106/μL) | 4.5 | 0.5 | 4.6 | 0.5 | 4.6 | 0.5 | 4.6 | 0.5 |
| Red cell distribution width (%) | 13.3 | 1.6 | 13.3 | 1.6 | 13.6 | 1.6 | 14.9 | 2.3 |
| Mean corpuscular volume (fL) | 83.8 | 7.0 | 80.9 | 7.3 | 78.1 | 6.4 | 72.8 | 8.0 |
Lower limit of detection is imputed for undetectable results