Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Dec 30;13(1):89. doi: 10.3390/nu13010089

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Effects of maternal pre- and post-conception diet on the hypothalamic satiety system. (A) Neuropeptide Y (NPY) density in the arcuate nucleus (ARC), males. (B) ARC NPY density, females. (C) Paraventricular nucleus (PVN) NPY density, males. (D) PVN NPY density, females. (E) Representative photomicrographs of NPY-positive cells in the ARC, males. Scale bar = 50 μm. (F) Npy mRNA, males. (G) Npy mRNA, females. (H) Agouti-related peptide (Agrp) mRNA, males. (I) Agrp mRNA, females. (J) Pro-opiomelanocortin (Pomc) mRNA, males. (K) Pomc mRNA, females. (L) Leptin receptor (Lepr) mRNA, males. (M) Lepr mRNA, females. (N) Growth hormone secretagogue receptor (Ghsr) mRNA, males. (O) Ghsr mRNA, females. HFSD: high-fat-high-sugar diet; Ch: chow (in D). Letters denote post hoc differences between groups; * significant effect of post-conception diet; ^# significant effect of pre-conception diet (p < 0.05). Data are mean ± SEM (n = 3–10). Each data point represents one pup per litter per sex.