Figure 2.

Arterial, venous, and arterial-venous (A-V) differences in (a) glucose and (b) lactate (right) concentrations prior to (PRE) and during the course of [U-¹³C] glucose infusion. Error bars are standard deviation (n = 5; 2 males and 3 females). # indicates statistically significance (“PRE” vs. “10 min.”; p < 0.05; two–tailed Student’s t–test). Glucose and lactate concentrations were measured as described in Methods section. (c) Fractions of acetyl-CoA without ¹³C enrichment (Fc0) and enriched at both carbons of the acetyl group (Fc3) estimated from ¹³C NMR spectra (Figure 1).