Table 1.
Group | VC | DEP | LPS | DEP + LPS |
---|---|---|---|---|
Black pigmented macrophages | 0 | 3.2 ± 0.45 ## | 0 | 3.4 ± 0.55 ** |
Granulomatous inflammation/pulmonary fibrosis | 0 | 0.4 ± 0.55 | 0.4 ± 0.55 | 1.8 ± 0.45 ** |
Acute inflammation, alveolar/interstitial | 0 | 0 | 2.6 ± 1.52 ## | 3.8 ± 0.45 |
Infiltrate, neutrophilic cells, alveolar | 0 | 0 | 3.2 ± 0.84 ## | 3.6 ± 0.55 |
1: minimal; 2: slight; 3: moderate; 4: severe. Data are presented as means ± SD for five mice per group. DEP, diesel exhaust particulate. ## p < 0.001 vs. VC; ** p < 0.001 vs. LPS.