Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jan 11;10(1):124. doi: 10.3390/cells10010124

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Schematic drawing of PRMT5-PTEN axis. Akt = Protein kinase B; CDK2 = Cyclin-dependent kinase 2; GBM = Glioblastoma; HDAC = Histone deacetylase; PIP2 = Phosphatidylinositol (4,5)-bisphosphate; PIP3 = Phosphatidylinositol (3,4,5)-triphosphate; P = Phosphorous; PTEN = Phosphatase and tensin homolog; PI3K = Phosphoinositide-3-kinase; PRMT5 = Protein arginine methyltransferase 5; RB = Retinoblastoma. Adapted from “G1/S Checkpoint”, by BioRender.com (2020). Retrieved from https://app.biorender.com/biorender-templates.