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. 2021 Jan 15;26(2):431. doi: 10.3390/molecules26020431

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Scheme 4 — Putative SAR and structure–solubility relationship considerations for the analogues of 22 reported in [78,80] (IEGCL: inhibitory effect in growth of tumor cell lines).