Fig. 1.

Morphology changes in TLE appear similar to those in healthy ageing. (A) Morphology changes in TLE in the ipsilateral hemisphere compared to a control cohort measured as z-scores. Violin plots show the distribution of bootstrapped mean z-scores. Age and sex correction was performed before the comparison. (B) Morphology changes in healthy ageing comparing a younger and older group of adult subjects, measured as z-scores relative to the younger subject group. Violin plots show the distribution of bootstrapped mean z-scores. Sex correction was performed before the comparison. (A & B) All morphological measures are in terms of a whole cortical hemisphere and log-scaled before analysis. Each hemisphere was treated as a separate datapoint. * denotes statistical significance at $p<0.05$. Beeswarm plots with raw data points are presented in Supplementary Data.