Table 2.

Human lipid, and inflammatory profiles.

	Placebo (n = 48)				B. longum APC1472 (n = 74)				Placebo vs B. Longum APC1472
Variable	Week 0	Week 6	Week 12	P-value Week 0–12	Week 0	Week 6	Week 12	P-value Week 0–12	Difference (95% CI)	P-value	η2
Lipid profile
Cholesterol (mmol/L)	5.50 ± 0.12	5.42 ± 0.13	5.34 ± 0.15	0.310	5.45 ± 0.12	5.48 ± 0.12	5.41 ± 0.10	0.691	0.094 (−0.22 to 0.41)	0.556	0.003
Triglycerides (mmol/L)	1.50 ± 0.13	1.47 ± 0.11	1.41 ± 0.09	0.412	1.46 ± 0.10	1.43 ± 0.08	1.49 ± 0.10	0.778	0.089 (−0.14 to 0.31)	0.432	0.005
LDL (mmol/L	3.72 ± 0.13	3.70 ± 0.12	3.75 ± 0.15	0.896	3.73 ± 0.12	3.81 ± 0.11	3.66 ± 0.10	0.473	−0.083 (−0.38 to 0.21)	0.579	0.003
HDL (mmol/L)	1.33 ± 0.04	1.34 ± 0.05	1.29 ± 0.05	0.537	1.29 ± 0.04	1.32 ± 0.04	1.36 ± 0.04	0.039	0.091 (−0.01 to 0.19)	0.074	0.027
Inflammatory profile
IL-10 (pg/ml)	0.43 ± 0.06	0.46 ± 0.06	0.42 ± 0.05	0.696	0.36 ± 0.03	0.38 ± 0.03	0.38 ± 0.05	0.807	−0.012 (−0.15 to 0.13)	0.864	<0.001
TNF-α (pg/ml)	1.14 ± 0.10	1.18 ± 0.12	1.04 ± 0.09	0.236	0.90 ± 0.06	0.88 ± 0.06	0.86 ± 0.06	0.488	−0.013 (−0.14 to 0.11)	0.838	<0.001
IFNγ (pg/ml)	9.24 ± 1.38	9.21 ± 1.11	9.6 ± 1.6	0.819	6.80 ± 0.78	5.76 ± 0.50	9.4 ± 3.0	0.383	−0.017 (8.29 to 8.26)	0.997	<0.001