Figure 5.

Activated healthy cells functionally present TAP-independent peptides

(A) T cell coculture with healthy donor PBMCs activated for 3 days with IFN-γ.

(B) T cell coculture with healthy donor B cells activated using CpG and B cell receptor cross-linking antibodies.

(C) T cell coculture with HLA-A2 positive and negative HUVECS activated with IFN-γ. Culture supernatants were analyzed using GM-CSF ELISA. Results from triplicate cultures are shown. Dotted lines represent lower and upper detection limit of the ELISAs.

See also Figure S4.