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Elsevier - PMC COVID-19 Collection logoLink to Elsevier - PMC COVID-19 Collection
. 2021 Feb 1;147(2):AB79. doi: 10.1016/j.jaci.2020.12.303

COVID-19 pandemia: Atopy and prospective analysis of the clinical evolution of patients infected with the SARS-CoV-2 virus

Débora S Guterres 1, Ana Carolina Dos Santos 2, Marina de Almeida Prado Meireles Laubi 2, Marina Laubi 2, Roselene Lourenço 1, Marcus Vinícius 1, Rosana Agondi 3, Ana Karolina Marinho 4, Valéria Brandão 5, Thais Saito 5, Grasiela Lima 5
PMCID: PMC7849529

Rationale

A few scientific evidence is now available to date on the clinical evolution of COVID-19 in atopics. The aim of this study was to assess the frequency of atopy in patients hospitalized for COVID-19.

Methods

A prospective study was carried out with hard descriptive data of 4 months. During this period, 300 patients were admitted with ARS and positive RT-PCR for SARS-CoV-2. Clinical features, history of atopy, total IgE and chest tomography were evaluated.

Results

Of all patients, 212 (70%) were male and the average age was 58 years old. Of the total, 37 patients (12.3%) had a history of atopy according to the following: 19 rhinitis (51.4%), 15 asthma (40.5%) and 3 (1%), atopic dermatitis. Obesity was present in 32% of the evaluated atopics. The mean of atopic patients was aged for 55, 92% O2 Sat, respiratory rate 27 per minute, CT > 50% in 22 patients (7.3%) and 3 patients died (1%). Of these who died, all were elderly (age over 60 years) and had comorbidities such as SH and obesity. Mean IgE total was 538UI/ml, and 3 patients presented IgE above 2000, all of them with clinical suggesting atopy (AD, asthma and rhinitis).

Conclusions

The literature reports less severe outcomes in atopic patients affected by COVID-19. In the studied group, the frequency of atopy was lower than that observed in the literature for the general population and the tomographic impairment was lower than that of the non-atopic group. The atopic patients who died were elderly and had comorbidities.

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Articles from The Journal of Allergy and Clinical Immunology are provided here courtesy of Elsevier

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