Correction to: Psychopharmacology
10.1007/s00213-018-5119-x
The original version of this article included the following paragraph (p. 1161), which was incorrect:
"The manufacturer of the drug product was Onyx Scientific Limited UK, to cGMP standards. Onyx Scientific Limited UK also undertook the pharmaceutical form development work to establish the optimal process for the manufacturer of the three doses of LSD. The doses were made by the pharmacy at the clinical trial facility under their manufacturing licence conditions and following the process outlined in the IMPD. A manual containing detailed instructions for the storage, manufacture of the doses, dispensing, and reconciliation was followed and worksheets were monitored by an independent clinical research associate during the study. LSD tartrate was prepared as a solution in distilled water. Placebo was distilled water only (indistinguishable from the LSD solution). Stability testing was done for a 6-month period."
The correct paragraph is presented here:
"The manufacturer of the drug product was Onyx Scientific Limited UK, to cGMP standards. The doses were made by the pharmacy at the clinical trial facility under their manufacturing licence conditions and following the process outlined in the Investigational Medicinal Product Dossier (IMPD). A manual containing detailed instructions for the storage, manufacture of the doses, dispensing, and reconciliation was followed and worksheets were monitored by an independent clinical research associate during the study. D-Lysergic acid diethylamide (D-LSD, HPLC purity > 99%) was dissolved in ethanol at 25 mg/mL and prepared as a solution 50 μg or 2 μg D-LSD/mL in distilled water and completed to a final volume of 10 mL distilled water for oral administration. A shelf life of 78 hours was allocated to the doses, when stored in the defined container closure at a temperature of 2–8 °C, with the start of the expiry period being defined as the time of combining the D-LSD with ethanol. Placebo was distilled water only (indistinguishable from the LSD solution)."
Footnotes
The online version of the original article can be found at 10.1007/s00213-018-5119-x
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