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. 2021 Jan 29;26(3):702. doi: 10.3390/molecules26030702

Table 4.

Uses and properties of main phenolic compounds found in Mexican oregano extracts from different regions of Jalisco state.

Compound Importance
Flavanones
Pinocembrin Naturally found in honey and propolis. Pinocembrin has shown anti-inflammatory, antioxidant, antiapoptotic, antimicrobial and vasodilator activity and antiproliferative properties [28]. There are reports of protective activity against cerebral ischemia. Likewise, there are several studies of application technologies and pharmaceutical use [29,30,31].
Naringenin Antioxidant, anti-inflammatory, carbohydrate metabolism promoter and immune system modulator. Naringenin has high capacity to reduce plasma cholesterol level and useful for the treatment of hepatitis C [32]. Antimetastatic, naringenin stimulates DNA repair [33].
Eriodictyol It is extracted from yerba santa (Eriodictyon californicum). Eriodictyol has potential use in Parkinsons treatment [9].
Flavonols
Galangin It is found in high concentrations in Alpinia officinarum and Helichrysum aureonitens. Galangin has antiviral and antibacterial properties [9].
Quercetin It is found in high concentrations in onions. Presents antihistamine activity and antimutagenic, proapoptotic, antiangiogenic, antimetastatic properties and is a modulator of epigenetic changes [34].
Flavones
Genkwanin Antioxidant and antitumoral activities [35]. This is swine fever inhibitor [36].
Hispidulin It has only been reported in Rosmarinus officinalis. Presents antihepatotoxic, cough suppressant, platelet aggregation inhibitor activities and anticancer properties in liver cells [37].
Apigenin 7-O-glucoside Anti-inflammatory, antioxidant and antihemolysis [28]. Antimutagenic, pro-apoptotic, anti-angiogenic, anti-metastatic [38,39].
Flavanonols
Taxifolin Protective action of vascular system, anticancer. Promotes formation and stabilization of collagen fibrils [9].
Chalcones
Phlorizin It is found in high concentration in cultivated apples, their leaves and the bark of the roots from where it is obtained in crystalline form. It produces glycosuria in animals [9].