Table 3.
Main pharmacokinetics parameters of PUE after oral administration of the RP extracts with water, Bet-Maa and L-Pro-Maa.
| Parameters | PUE | ||
|---|---|---|---|
| Water | Bet-Maa | L-Pro-Maa | |
| Tmax (h) | 0.5 | 0.25 | 0.25 |
| Cmax (mg/L) | 2.248 ± 0.552 | 4.757 ± 0.854 * | 7.267 ± 0.432 * |
| T1/2z (h) | 6.146 ± 1.621 | 5.143 ± 0.817 | 7.281 ± 3.934 |
| AUC(0–t) (mg/L × h) | 2.623 ± 0.642 | 7.453 ± 1.267 * | 11.869 ± 2.181 * |
| AUC (0–∞) (mg/L × h) | 3.243 ± 0.742 | 9.483 ± 1.897 | 16.48 ± 5.714 * |
| MRT(0–t) (h) | 2.681 ± 0.047 | 3.122 ± 0.163 | 2.405 ± 0.689 |
| Fr (%) | 100 | 212 | 323 |
*: p < 0.05 compared with water group.