Antonio Bruno
Antonio Bruno
1Synaptic Immunopathology Lab, Department of Systems Medicine, Tor Vergata University of Rome, Rome, Italy
1,†,
Ettore Dolcetti
Ettore Dolcetti
1Synaptic Immunopathology Lab, Department of Systems Medicine, Tor Vergata University of Rome, Rome, Italy
1,†,
Francesca Romana Rizzo
Francesca Romana Rizzo
1Synaptic Immunopathology Lab, Department of Systems Medicine, Tor Vergata University of Rome, Rome, Italy
1,
Diego Fresegna
Diego Fresegna
2Synaptic Immunopathology Lab, IRCCS San Raffaele Pisana, Rome, Italy
2,
Alessandra Musella
Alessandra Musella
2Synaptic Immunopathology Lab, IRCCS San Raffaele Pisana, Rome, Italy
3Department of Human Sciences and Quality of Life Promotion, University of Rome San Raffaele, Rome, Italy
2,3,
Antonietta Gentile
Antonietta Gentile
2Synaptic Immunopathology Lab, IRCCS San Raffaele Pisana, Rome, Italy
2,
Francesca De Vito
Francesca De Vito
4Unit of Neurology, Mediterranean Neurological Institute IRCCS Neuromed, Pozzilli, Italy
4,
Silvia Caioli
Silvia Caioli
1Synaptic Immunopathology Lab, Department of Systems Medicine, Tor Vergata University of Rome, Rome, Italy
1,
Livia Guadalupi
Livia Guadalupi
1Synaptic Immunopathology Lab, Department of Systems Medicine, Tor Vergata University of Rome, Rome, Italy
1,
Silvia Bullitta
Silvia Bullitta
1Synaptic Immunopathology Lab, Department of Systems Medicine, Tor Vergata University of Rome, Rome, Italy
2Synaptic Immunopathology Lab, IRCCS San Raffaele Pisana, Rome, Italy
1,2,
Valentina Vanni
Valentina Vanni
1Synaptic Immunopathology Lab, Department of Systems Medicine, Tor Vergata University of Rome, Rome, Italy
2Synaptic Immunopathology Lab, IRCCS San Raffaele Pisana, Rome, Italy
1,2,
Sara Balletta
Sara Balletta
1Synaptic Immunopathology Lab, Department of Systems Medicine, Tor Vergata University of Rome, Rome, Italy
1,
Krizia Sanna
Krizia Sanna
1Synaptic Immunopathology Lab, Department of Systems Medicine, Tor Vergata University of Rome, Rome, Italy
1,
Fabio Buttari
Fabio Buttari
4Unit of Neurology, Mediterranean Neurological Institute IRCCS Neuromed, Pozzilli, Italy
4,
Mario Stampanoni Bassi
Mario Stampanoni Bassi
4Unit of Neurology, Mediterranean Neurological Institute IRCCS Neuromed, Pozzilli, Italy
4,
Diego Centonze
Diego Centonze
1Synaptic Immunopathology Lab, Department of Systems Medicine, Tor Vergata University of Rome, Rome, Italy
4Unit of Neurology, Mediterranean Neurological Institute IRCCS Neuromed, Pozzilli, Italy
1,4,*,
Georgia Mandolesi
Georgia Mandolesi
2Synaptic Immunopathology Lab, IRCCS San Raffaele Pisana, Rome, Italy
3Department of Human Sciences and Quality of Life Promotion, University of Rome San Raffaele, Rome, Italy
2,3
1Synaptic Immunopathology Lab, Department of Systems Medicine, Tor Vergata University of Rome, Rome, Italy
2Synaptic Immunopathology Lab, IRCCS San Raffaele Pisana, Rome, Italy
3Department of Human Sciences and Quality of Life Promotion, University of Rome San Raffaele, Rome, Italy
4Unit of Neurology, Mediterranean Neurological Institute IRCCS Neuromed, Pozzilli, Italy
✉*Correspondence: Diego Centonze centonze@uniroma2.it
Approved by: Frontiers Editorial Office, Frontiers Media SA, Switzerland
This article was submitted to Cellular Neuropathology, a section of the journal Frontiers in Cellular Neuroscience
†These authors share first authorship
Received 2020 Dec 29; Accepted 2020 Dec 30; Collection date 2020.
Keywords: multiple sclerosis, major depressive disorder, excitotoxicity, antidepressant drugs, cytokines, synaptopathy, neuroinflammation, monoamine
Copyright © 2021 Bruno, Dolcetti, Rizzo, Fresegna, Musella, Gentile, De Vito, Caioli, Guadalupi, Bullitta, Vanni, Balletta, Sanna, Buttari, Stampanoni Bassi, Centonze and Mandolesi.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
