Figure 3.

gB vaccination induces IgG and IgA responses to gB and AD‐2 in sero‐positive recipients. Serum samples obtained from the recombinant gB vaccination trial were analysed for IgG and IgA binding to gB and AD‐2 by ELISA. Individuals were stratified into (A) sero‐positive (IgG+to gB) and (B) sero‐negative (IgG‐ to gB). Statistical differences between the mean OD values of day 0 and 56 of vaccine recipients for IgG and IgA for binding to gB and AD‐2 epitope were obtained from the Mann–Whitney test (ns, not significant; *P < 0.05; ****P < 0.0001). Placebo groups showed no significant differences