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. Author manuscript; available in PMC: 2021 Feb 17.
Published in final edited form as: Cancer Cell. 2020 Dec 10;39(1):122. doi: 10.1016/j.ccell.2020.11.015

Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma

Catherine S Grasso *, Jennifer Tsoi, Mykola Onyshchenko, Gabriel Abril-Rodriguez, Petra Ross-Macdonald, Megan Wind-Rotolo, Ameya Champhekar, Egmidio Medina, Davis Y Torrejon, Daniel Sanghoon Shin, Phuong Tran, Yeon Joo Kim, Cristina Puig-Saus, Katie Campbell, Agustin Vega-Crespo, Michael Quist, Christophe Martignier, Jason J Luke, Jedd D Wolchok, Douglas B Johnson, Bartosz Chmielowski, F Stephen Hodi, Shailender Bhatia, William Sharfman, Walter J Urba, Craig L Slingluff Jr, Adi Diab, John BAG Haanen, Salvador Martin Algarra, Drew M Pardoll, Valsamo Anagnostou, Suzanne L Topalian, Victor E Velculescu, Daniel E Speiser, Anusha Kalbasi, Antoni Ribas *
PMCID: PMC7885306  NIHMSID: NIHMS1657061  PMID: 33306984

In this article, we report that T cell-induced interferon-γ correlates to response to immune checkpoint blockade therapy in melanoma patients. We would like to provide two additional supplemental tables. Table S1 details unidentifiable demographic information of patients to facilitate the re-analysis of the data based on specific patient characteristics or subgroups of melanomas. Table S2 contains the 549 interferon-γ-induced genes in melanoma cell lines that are mentioned in the article. These supplemental tables are now cited in the online version of the article and are provided with this article online.

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