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. Author manuscript; available in PMC: 2021 Feb 19.
Published in final edited form as: Hepatology. 2019 Apr 25;70(1):389–402. doi: 10.1002/hep.30612

Fig. 7. Relative mRNA levels of hepatic enzymes involved in BA synthesis for male WT, Cyp7a1−/−, Cyp27a1−/−, and DKO mice with FXR activation.

Fig. 7.

Mice were treated with vehicle or a synthetic FXR agonist, GW4064. The expression of genes at mRNA levels was measured using RT q-PCR and normalized to β-actin mRNA levels, and graphed as relative mRNA ± 1 SD. An asterisk denotes a significant difference from WT vehicle treated mice, an octothorpe denotes a significant difference between vehicle and GW4064 treatments (P < 0.05).