Table 1.
Summary of descriptive statistics for clinical data, histopathology characteristics and IPs including SN, AST, MST and other melanocytic diagnostic categories (HN, BN, CMM and NCN)
| Melanocytic diagnostic category | SN | AST | MST | HN | BN | NCN | CMM |
|---|---|---|---|---|---|---|---|
| Study number (n) | 50 | 17 | 12 | 25 | 22 | 20 | 20 |
| Age (years) | |||||||
| Mean | 25.4 | 32.3 | 47.2 | 30.6 | 51.7 | 48.6 | 68.6 |
| SEM | 1.7 | 4.1 | 6.6 | 4.4 | 4.4 | 3.5 | 3.2 |
| Median | 24.0 | 26.0 | 49.5 | 28.0 | 49.5 | 52.5 | 73.0 |
| SD | 12.0 | 16.8 | 22.7 | 18.4 | 20.5 | 15.5 | 14.3 |
| Minimum | 1 | 13 | 10 | 10 | 19 | 21 | 32 |
| 25th centile | 19.0 | 23.0 | 32.5 | 17.75 | 38.0 | 33.0 | 66.5 |
| 75th centile | 31.3 | 37.0 | 59.0 | 36.0 | 68.75 | 58.25 | 79.0 |
| Maximum | 55 | 71 | 86 | 82 | 84 | 72 | 88 |
| Gender | |||||||
| Female | 34 | 15 | 5 | 13 | 12 | 8 | 11 |
| Male | 16 | 2 | 7 | 5 | 10 | 12 | 9 |
| NA | 0 | 0 | 0 | 7 | 0 | 0 | 20 |
| Anatomical site | |||||||
| Upper extremities | 11 | 5 | 4 | 0 | 8 | 1 | 4 |
| Lower extremities | 19 | 4 | 3 | 0 | 4 | 0 | 4 |
| Corpus | 9 | 7 | 3 | 16 | 3 | 18 | 7 |
| Head/neck | 10 | 1 | 2 | 2 | 7 | 1 | 5 |
| NA | 1 | 0 | 0 | 7 | 0 | 0 | 0 |
| Histological features | |||||||
| Junctional | 7 (14%) | 0 | 0 | 0 (0%) | 0 (0%) | 2 (10%) | 0 (0%) |
| Dermal | 5 (10%) | 0 | 0 | 1 (4%) | 22 (100%) | 2 (10%) | 0 (0%) |
| Compound | 38 (76%) | 17 (100%) | 12 (100%) | 25 (95%) | 0 (0%) | 16 (80%) | 20 (100%) |
| Lesion diameter (mm) | |||||||
| Mean | 4.3 | 5.6 | 7.2 | 5.5 | 4.7 | 6.7 | 13.2 |
| SEM | 0.2 | 0.7 | 0.8 | 0.6 | 0.6 | 0.6 | 2.1 |
| Median | 4.0 | 5.0 | 6.0 | 5.0 | 4.0 | 6.0 | 9.5 |
| SD | 1.7 | 2.7 | 2.9 | 2.4 | 2.9 | 2.7 | 9.3 |
| Minimum | 1.8 | 2.5 | 5.0 | 2.0 | 1.0 | 2.0 | 3.0 |
| 25th centile | 3.0 | 4.0 | 5.8 | 4.0 | 3.0 | 4.8 | 6.0 |
| 75th centile | 5.0 | 7.0 | 7.3 | 7.0 | 5.5 | 8.3 | 18.5 |
| Maximum | 9.0 | 13.0 | 15.0 | 11.0 | 15.0 | 12.0 | 32.0 |
| IP score | |||||||
| IP0 | 4 (8%) | 0 (0%) | 1 (8.3%) | 0 (0%) | 18 (81.8%) | 3 (15%) | 1 (5%) |
| IP1 | 11 (22%) | 5 (29.4%) | 5 (41.7%) | 0 (0%) | 4 (18.2%) | 10 (50%) | 7 (35%) |
| IP2 | 33 (66%) | 7 (41.2%) | 3 (25%) | 0 (0%) | 0 (0%) | 6 (30%) | 7 (35%) |
| IP3 | 2 (4%) | 5 (29.4%) | 3 (25%) | 25 (100%) | 0 (0%) | 1 (5%) | 5 (25%) |
| Mean follow‐up (years) | |||||||
| Mean | 4.6 | 3.8 | 5.2 | 6.5 | 1.2 | 1.3 | 1.7 |
| SEM | 0.3 | 0.6 | 1.2 | 0.9 | 0.1 | 0.1 | 0.1 |
| Median | 4.0 | 3.0 | 4.0 | 7.0 | 1.0 | 1.0 | 2.0 |
| SD | 2.3 | 2.4 | 4.0 | 4.3 | 0.4 | 0.6 | 0.5 |
| Minimum | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 25th centile | 3.0 | 3.0 | 1.8 | 2.0 | 1.0 | 1.0 | 1.0 |
| 75th centile | 6.0 | 5.0 | 8.3 | 10.0 | 1.0 | 1.3 | 2.0 |
| Maximum | 12 | 11 | 12 | 13 | 2 | 3 | 2 |
| Local recurrence | |||||||
| Yes | 1 (2%) | 1 (5.9%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 4 (20%) |
| No | 49 (98%) | 16 (94.1%) | 12 (100%) | 18 (72%) | 22 (100%) | 20 (100%) | 16 (80%) |
| NA | 0 (0%) | 0 (0%) | 0 (0%) | 7 (28%) | 0 (0%) | 0 (0%) | 0 (0%) |
AST, Atypical Spitz tumour; BN, Blue naevus; HN, Halo naevus; CMM, Cutaneous malignant melanoma; mm, Millimetre; MST, Malignant Spitz tumour; n = Number; NA, Not available; NCN, Naevocellular naevus; SEM, Standard error of the mean; SD, Standard deviation; SN, Spitz naevus.