Table 3.

Inhibition of SARS‐CoV‐2 replication in Vero E6 cells and cytotoxicity in Vero E6 cells using a selection of benzamide and isoindoline inhibitors. Selectivity indices (SI) were calculated using the CC₅₀ and EC₅₀ values determined for the respective compounds.

Compd	Class	EC50 [μM][a]	CC50 [μM][a]	SI
2 i	Benzamide	1.77±1.60	376±1.36	212
2 n		4.74±1.35	>500	>105
2 p		15.75±1.59	>500	>31.7
14 h	Isoindoline	7.85±1.50	442±1.37	56.3
14 k		n.a.	>500	‐

[a] Experiments were performed in biological triplicates. Data are reported as mean±standard deviation.