Table 3:
Multivariable Regression Models for 30, 90, and 180-day Post-Operative Mortality
| Variable | Odds Ratio | 95% Confidence Interval | P-value |
|---|---|---|---|
| 30-day Post-Operative Mortality Model | |||
| ASA Class (Ordinal; 2, 3, or 4) | 2.89 | (1.84 – 4.54) | <0.001* |
| Emergency Procedure | 2.53 | (1.54 – 4.16) | <0.001* |
| Surgery Category | 0.012* (joint) | ||
| Abdominal – Laparoscopic | 1.0 (Ref) | ||
| Abdominal – Open | 4.76 | (0.89 – 25.54) | 0.069 |
| Abdominal Wall | 2.10 | (0.39 – 11.23) | 0.386 |
| Vascular | 2.50 | (0.42 – 14.95) | 0.315 |
| Major Orthopedic | 4.32 | (0.82 – 22.69) | 0.083 |
| Chest/Cardiac | 6.64 | (1.20 – 36.64) | 0.030* |
| Albumin (per 1 g/dL)‡ | <0.001* | ||
| Spline 1 | 0.60 | (0.36 – 0.98) | |
| Spline 2 | 0.37 | (0.13 – 1.08) | |
| Platelet Count (per 1,000/μL)‡ | 0.002* | ||
| Spline 1 | 0.99 | (0.99 – 1.00) | |
| Spline 2 | 1.00 | (0.99 – 1.01) | |
| Total Bilirubin (per 1 mg/dL) | 1.16 | (1.06 – 1.26) | 0.001* |
| Etiology of Cirrhosis | |||
| Non-NAFLD | 1.0 (Ref) | ||
| NAFLD | 2.29 | (1.37 – 3.82) | 0.002* |
| Obesity (body mass index ≥30) | 0.47 | (0.30 – 0.74) | 0.001* |
| 90-day Post-Operative Mortality Model | |||
| ASA Class (Ordinal; 2, 3, or 4) | 1.99 | (1.33 – 2.99) | 0.001* |
| Emergency Procedure | 1.87 | (1.12 – 3.12) | 0.017* |
| Surgery Category | 0.015* (joint) | ||
| Abdominal – Laparoscopic | 1.0 (Ref) | ||
| Abdominal – Open | 3.86 | (1.12 – 13.25) | 0.032* |
| Abdominal Wall | 1.28 | (0.36 – 4.56) | 0.702 |
| Vascular | 2.87 | (0.81 – 10.17) | 0.102 |
| Major Orthopedic | 2.91 | (0.88 – 9.66) | 0.081 |
| Chest/Cardiac | 3.54 | (0.99 – 12.75) | 0.053 |
| Age (per year) | 3.86 | (1.12 – 13.25) | 0.008* |
| Albumin (per 1 g/dL)‡ | <0.001* | ||
| Spline 1 | 0.62 | (0.38 – 1.00) | |
| Spline 2 | 0.37 | (0.15 – 0.94) | |
| Etiology of Cirrhosis | |||
| Non-NAFLD | 1.0 (Ref) | ||
| NAFLD | 2.29 | (1.44 – 3.63) | <0.001* |
| 180-day Post-Operative Mortality Model | |||
| ASA Class (Ordinal; 2, 3, or 4) | 2.34 | (1.46 – 3.74) | <0.001* |
| Surgery Category | 0.270† (joint) | ||
| Abdominal – Laparoscopic | 1.0 (Ref) | ||
| Abdominal – Open | 2.42 | (0.79 – 7.38) | 0.120 |
| Abdominal Wall | 1.22 | (0.40 – 3.68) | 0.726 |
| Vascular | 1.59 | (0.49 – 5.14) | 0.440 |
| Major Orthopedic | 1.13 | (0.37 – 3.44) | 0.829 |
| Chest/Cardiac | 1.54 | (0.45 – 5.31) | 0.494 |
| Age (per year) | 1.03 | (1.00 – 1.06) | 0.073† |
| Platelet Count (per 1,000/μL)‡ | 0.057† | ||
| Spline 1 | 1.00 | (0.99 – 1.00) | |
| Spline 2 | 1.00 | (0.99 – 1.01) | |
| Albumin (per 1 g/dL)‡ | 0.001* | ||
| Spline 1 | 0.63 | (0.35 – 1.15) | |
| Spline 2 | 0.66 | (0.26 – 1.69) | |
| Obesity (body mass index ≥30) | 0.60 | (0.36 – 0.98) | 0.040* |
Abbreviations: ASA = American Society of Anesthesiologists; NAFLD = non-alcoholic fatty liver disease
*
Significant at the p<0.05 level
†
This variable was retained on the basis of minimized Aikake Information Criterion and Bayesian Information Criterion values
‡
Joint hypothesis tests were performed to test the statistical significance of variables modeled using restricted cubic splines