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. 2021 Feb 23;325(8):753–764. doi: 10.1001/jama.2021.0507

Table. Baseline Participant Characteristics in the Discovery Cohorta.

Characteristic With exfoliation syndrome Without exfoliation syndrome
Japanb
No. analyzed 3806 4197
Age, median (IQR), y 78 (73-83) 74 (68-79)
Sex, No. (%)
Female 2280 (59.9) 2468 (58.8)
Male 1526 (40.1) 1729 (41.2)
Exfoliation glaucoma, No. (%) 2180 (57.3) 0
Self-reported ancestry Japanese Japanese
No. of participants 3806 4197
Singaporeb
No. analyzed 172 1288
Age, median (IQR), y 79 (73-85) 67 (63-73)
Sex, No. (%)
Female 76 (44.2) 612 (47.5)
Male 96 (55.8) 676 (52.5)
Exfoliation glaucoma, No. (%) 82 (47.7) 0
Self-reported ancestry Chinese Chinese
No. of participants 172 1288
South Africab
No. analyzed 50 153
Age, median (IQR), y 71 (67-77) 69 (63-76)
Sex, No. (%)
Female 21 (42.0) 79 (51.6)
Male 29 (58.0) 74 (48.4)
Exfoliation glaucoma, No. (%) 47 (94.0) 0
Self-reported ancestry Black African Black African
No. of participants 50 153

Abbreviation: IQR, interquartile range.

a

All participants underwent whole-exome sequencing.

b

Indicates the country where participants were recruited.