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. 2021 Jan 31;10(2):283. doi: 10.3390/cells10020283

Table 1.

Clinical phenotypes frequently reported in PD cases with PARK2 mutations [97,100,102,103].

Clinical Phenotype
Motor features Bradykinesia
Resting tremor
Non-motor features Anxiety
Psychosis
Panic attack
Depression
Other clinical features Normal cognitive function
Hyperreflexia
Frequent focal dystonia
Sleep benefit
Benign disease course
Excellent response to low dose Levodopa
Prone to develop Levodopa-induced dyskinesias