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. 2021 Jan 21;9(2):103. doi: 10.3390/biomedicines9020103

Figure 8.

Figure 8

Predicted IRE in SFXN transcripts. (A). Two IREs were found in the 3′UTR of SFXN1 transcripts using the SIREs Web Server 2.0. The first one is located at the end of the coding sequence. (B). Alignment showing the position of the two IREs in SFXN1 transcripts. All except one shorter SFXN1 transcript variant possess putative IREs. (C). Alignment of the IREs of DMT-1, transferrin receptor (TFRC) and SFXN1 transcripts using MultiAlin. The consensus highlights the position of the six-nucleotide apical loop (5′-CAGWGH-3′) as shown in the yellow box. D, E. Schemes (D) and RNA fold prediction (E) for the IREs from TFRC, DMT-1, SFXN1 and SFXN5 transcripts generated by the SIREs Web Server 2.0.