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. Author manuscript; available in PMC: 2022 Feb 2.
Published in final edited form as: Circulation. 2020 Nov 9;143(5):410–423. doi: 10.1161/CIRCULATIONAHA.120.051775

Table 2.

Cumulative incidence of coronary artery disease events by premature menopause and clonal hematopoiesis status in the pooled cohort of the UK Biobank and Women’s Health Initiative.

No CHIP Any CHIP CHIP with VAF >0.1
No history of premature menopause 8.3%
(1,352/16,376)		 13.0%
(119/916)		 15.4%
(97/629)
History of premature menopause 12.5%
(132/1,056)		 15.5%
(16/103)		 17.3%
(14/81)

Cumulative incidences listed are over a median (IQR) follow-up of 10.0 (9.8–11.9) years among women without established coronary artery disease at the time of blood draw. P<0.001 by the Pearson chi-squared test. CHIP = clonal hematopoiesis of indeterminate potential; VAF = variant allele frequency.