Table 1.

Experimental accessibility and tools for vertebrate species used in regeneration research.

	Lizard				Salamander		Zebrafish
	A. carolinensis	E. macularius	G. japonicus	P. muralis	A. mexicanum	P. waltl	D. rerio
Experimental Accessibility
Genome Size	1.78 Gb	2.23 Gb	2.55 Gb	1.51 Gb	~32 Gb	~20 Gb	1.67 Gb
Fertilization	internal	internal	internal	internal	external	external	external
Egg Size	~6 mm	~12 mm [48]	~13 mm [49]	~11 mm [50]	~2 mm	~2 mm	<1 mm [51]
Egg Transparency	no	no	no	no	yes	yes	yes
Experimental Tools
Genome Annotation	Ensembl NCBI	NCBI	NCBI	Ensembl NCBI	NCBI	NCBI	Ensembl NCBI
Transcriptome Annotation	NCBI	NCBI	NCBI	NCBI	NCBI	NCBI	NCBI
Knock-down *	no	no	no	no	yes [31]	no	yes [46]
Transgenesis	no	no	no	no	yes [30,38]	yes [52]	yes [43,53]
Knock-out/Knock-in	no	no	no	no	yes [54] **	yes [55] **	yes [42,56] ** #

* = morpholino ** = CRISPR/Cas9 # = ENU mutagenesis.