Table 1.
The top 15 parameters with the greatest sum of sensitivity, specificity, and accuracy values. The parameters in bold were shown to significantly correlate with disease progression.
| Parameter | Sensitivity | Specificity | Accuracy | Sensitivity + Specificity + Accuracy |
|---|---|---|---|---|
| EV_ERCC1_appearance | 0.1765 | 0.9730 | 0.7222 | 1.8717 |
| EV_KIT_appearance | 0.1176 | 1.0000 | 0.7222 | 1.8399 |
| CTC_AR_appearance | 0.1765 | 0.9459 | 0.7037 | 1.8261 |
| CTC_ERBB3_appearance | 0.1765 | 0.9459 | 0.7037 | 1.8261 |
| CTC_ERBB3ORCTC_ERBB2 | 0.3636 | 0.8649 | 0.5926 | 1.8211 |
| cfDNA_PIK3CA_appearance | 0.1176 | 0.9730 | 0.7037 | 1.7943 |
| cfDNA_ERRB3ORCTC_ERBB3OREV_ERBB3 | 0.3182 | 0.8919 | 0.5802 | 1.7903 |
| CTC_BRCA1_appearance | 0.1765 | 0.9189 | 0.6852 | 1.7806 |
| EV_ERBB3_appearance | 0.1765 | 0.9189 | 0.6852 | 1.7806 |
| EV_SRC_appearance | 0.1765 | 0.9189 | 0.6852 | 1.7806 |
| cfDNA_FGFR1_appearance | 0.0588 | 1.0000 | 0.7037 | 1.7625 |
| EV_PIK3CA_appearance | 0.0588 | 1.0000 | 0.7037 | 1.7625 |
| CTC_AURKA_appearance | 0.1176 | 0.9459 | 0.6852 | 1.7488 |
| EV_AR_appearance | 0.1176 | 0.9459 | 0.6852 | 1.7488 |
| CTC_ERBB3 | 0.2273 | 0.9459 | 0.5556 | 1.7288 |